Malignant rhabdoid tumours (MRT) are a rare but very aggressive tumour that occurs in childhood. They are rare, with only a few cases a year in the UK. 80% of rhabdoid tumours have spread before children are diagnosed and as such, these children generally have poorer outcomes than the 20% that present with no evidence of spread. Each case however needs to be looked at on an individual basis, and new treatments are evolving.
Most commonly MRTs occur in the kidney (like Grace) and brain, but can occur anywhere in the body.
Characterised by specific cell changes in the tumour itself making it far more agressive than many other tumour types.
Other renal tumour types include:
Undifferentiated and clear cell sarcoma of the kidney
Renal cell carcinoma
Rhabdoid tumours can affect other areas of the body too including the brain and spine - atypical rhabdoid / teratoid tumours